{"id":13,"date":"2024-02-27T11:26:35","date_gmt":"2024-02-27T11:26:35","guid":{"rendered":"https:\/\/hansjirobecker.com\/imsut2024\/?page_id=13"},"modified":"2025-09-18T08:14:03","modified_gmt":"2025-09-18T08:14:03","slug":"publications","status":"publish","type":"page","link":"https:\/\/dcr-imsut.com\/index.php\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<div class=\"wp-block-cover alignfull is-light\" style=\"min-height:380px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-40 has-background-dim\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"960\" height=\"312\" class=\"wp-block-cover__image-background wp-image-246\" alt=\"\" src=\"https:\/\/hansjirobecker.com\/imsut2024\/wp-content\/uploads\/2024\/04\/slider03.jpg\" style=\"object-position:33% 18%\" data-object-fit=\"cover\" data-object-position=\"33% 18%\" srcset=\"https:\/\/dcr-imsut.com\/wp-content\/uploads\/2024\/04\/slider03.jpg 960w, https:\/\/dcr-imsut.com\/wp-content\/uploads\/2024\/04\/slider03-300x98.jpg 300w, https:\/\/dcr-imsut.com\/wp-content\/uploads\/2024\/04\/slider03-768x250.jpg 768w\" sizes=\"(max-width: 960px) 100vw, 960px\" \/><div class=\"wp-block-cover__inner-container has-global-padding is-layout-constrained wp-container-core-cover-is-layout-1 wp-block-cover-is-layout-constrained\">\n<div class=\"wp-block-group alignfull has-global-padding is-content-justification-center is-layout-constrained wp-container-core-group-is-layout-2 wp-block-group-is-layout-constrained\" style=\"min-height:0.4rem\">\n<div class=\"wp-block-group has-global-padding is-content-justification-center is-layout-constrained wp-container-core-group-is-layout-1 wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading has-text-align-left has-text-color\" style=\"color:#d2d2d2;margin-bottom:1rem;font-size:clamp(1.039rem, 1.039rem + ((1vw - 0.2rem) * 0.701), 1.6rem);font-style:normal;font-weight:400;line-height:1;text-transform:uppercase\"><\/h3>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-ibm-plex-sans-font-family\" style=\"color:#ffffff;margin-top:0rem;margin-bottom:0rem;font-size:clamp(1.743rem, 1.743rem + ((1vw - 0.2rem) * 1.571), 3rem);font-style:normal;font-weight:700;line-height:1.1;text-transform:uppercase\">PUBLICATION LIST<\/h2>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-global-padding is-layout-constrained wp-container-core-group-is-layout-4 wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:0;padding-top:5.51rem;padding-right:1rem;padding-bottom:3rem;padding-left:1rem\">\n<div class=\"wp-block-group alignwide has-global-padding is-layout-constrained wp-container-core-group-is-layout-3 wp-block-group-is-layout-constrained\" style=\"margin-top:1.01rem\">\n<h3 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-e80b4fb6d1ea9b55c6df61f11aa51525\" style=\"color:#858585;font-size:clamp(1.976rem, 1.976rem + ((1vw - 0.2rem) * 1.905), 3.5rem);text-transform:uppercase\"><strong>Publications<\/strong><\/h3>\n\n\n\n<div class=\"wp-block-query is-layout-flow wp-block-query-is-layout-flow\"><nav class=\"wp-block-query-pagination is-layout-flex wp-block-query-pagination-is-layout-flex\" aria-label=\"Pagination\">\n\n\n<div class=\"wp-block-query-pagination-numbers\"><span aria-current=\"page\" class=\"page-numbers current\">1<\/span>\n<a class=\"page-numbers\" href=\"?query-11-page=2\">2<\/a><\/div>\n\n<a href=\"\/index.php\/wp-json\/wp\/v2\/pages\/13?query-11-page=2\" class=\"wp-block-query-pagination-next\">Next Page<\/a>\n<\/nav>\n\n<ul class=\"wp-block-post-template is-layout-flow wp-container-core-post-template-is-layout-1 wp-block-post-template-is-layout-flow\"><li class=\"wp-block-post post-739 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">2026<\/h5>\n\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-741 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">A scalable two-step genome editing strategy for generating full-length gene-humanized mice at diverse genomic loci.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-1 wp-block-post-content-is-layout-flow\">\n<p>Taguchi J, Kikuchi M, Jeon H, Shimizu R, Mori H, Ikawa M, Yamada Y, Sato K, Ikeda T,\u00a0Yamazaki S, Ozawa M.\u00a0\u00a0<\/p>\n\n\n\n<p>Nat Commun. 2026 Jan 14;17(1):356. doi:10.1038\/s41467-025-67900-4.PMID:\u00a041535270<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-718 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">2025<\/h5>\n\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-714 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Low-input proteomics identifies vWF as a negative regulator of Tet2 mutant hematopoietic stem cell expansion<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-2 wp-block-post-content-is-layout-flow\">\n<p>Jassinskaja M, Bode D, Gonka M, Roumeliotis TI, Hogg AJ, Rubio Lara JA, Bennett E, Milek J, Elberfeld S, Theeuwes B, Vijayabaskar MS, Cosme LC, Chi Che JL, MacDonald S, Ahmed S, Hall BA, Vasey G, Kooi H, Belmonte M, Shepherd MS, Brackenbury WJ, Kucinski I,\u00a0Yamazaki S, Holding AN, Cull AH, Wilson NK, G\u00f6ttgens B, Choudhary J, Kent DG.<\/p>\n\n\n\n<p>Cell Rep. 2025 Dec 24;45(1):116770. doi: 10.1016\/j.celrep.2025.116770. Online ahead of print.PMID:\u00a041447537<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-712 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Prospective isolation of mouse and human hematopoietic stem cells using PLXDC2<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-3 wp-block-post-content-is-layout-flow\">\n<p>Tanaka Y, Kubota Y, Kikuchi R, Yabushita T, Kimura T, Lieberam I, Barlow JL, Bramley JW, Fukushima T, Sakuma C, Shibata T, Nakagawa M, Kurosawa Y, Maruyama T, Okumura CJ, Arima Y, Sato Y, Ono Y, Akuta T, Mizuno H, Kent DG, Jessell TM, Goyama S, Nishikii H, Kimura S,\u00a0Yamazaki S, Suda T, Kitamura T<\/p>\n\n\n\n<p>Commun Biol. 2025 Dec 10. doi: 10.1038\/s42003-025-09242-x. Online ahead of print.PMID:\u00a041372396\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-710 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Tumor necrosis factor from leukemic environment stimulates hematopoietic stem\/progenitor cells toward megakaryocyte\/myeloid lineage bias<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-4 wp-block-post-content-is-layout-flow\">\n<p>Nishikii H, Kikuchi R, Kimura T, Saito M, Kiyoki Y, Tanaka S, Sasaki Y, Kato T, Sakamoto T, Sakata-Yanagimoto M, Obara N,\u00a0Yamazaki S, Chiba S.<\/p>\n\n\n\n<p>Exp Hematol. 2025 Dec 4:105332. doi: 10.1016\/j.exphem.2025.105332. Online ahead of print.PMID:\u00a041352655<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-677 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Protocol for noninvasive imaging of hematopoietic reconstitution in live mice using Akaluc bioluminescence.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-5 wp-block-post-content-is-layout-flow\">\n<p>Yogo T, Yamazaki S.<\/p>\n\n\n\n<p>STAR Protoc. 2025 Sep 10;6(3):104072. doi: 10.1016\/j.xpro.2025.104072. Online ahead of print.PMID:\u00a040934075<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-659 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-6 wp-block-post-content-is-layout-flow\">\n<p>Yogo T, Iwamoto Y, Becker HJ, Kimura T, Ishida R, Sugiyama-Finnis A, Yokomizo T, Suda T, Ota S, Yamazaki S.<\/p>\n\n\n\n<p>Nat Commun. 2025 Jul 14;16(1):6496. doi: 10.1038\/s41467-025-61846-3.PMID:&nbsp;40659629<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-616 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Signaling networks in cancer stromal senescent cells establish malignant microenvironment<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-7 wp-block-post-content-is-layout-flow\">\n<p>Zhang Y, Wang TW, Tamatani M, Zeng X, Nakamura L, Omori S, Yamaguchi K, Hatakeyama S, Shimizu E,\u00a0Yamazaki S, Furukawa Y, Imoto S, Johmura Y, Nakanishi M<\/p>\n\n\n\n<p>Proc Natl Acad Sci U S A. 2025 Apr 8;122(14):e2412818122. doi: 10.1073\/pnas.2412818122. Epub 2025 Apr 1.PMID:\u00a040168129<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-618 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Hematopoietic stem cells undergo bidirectional fate transitions\u00a0in vivoShare\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-8 wp-block-post-content-is-layout-flow\">\n<p>Fukushima T, Kristiansen TA, Wong LP, Keyes S, Tanaka Y, Mazzola M, Zhao T, He L, Yagi M, Hochedlinger K,\u00a0Yamazaki S, Sadreyev RI, Scadden DT.<\/p>\n\n\n\n<p>bioRxiv [Preprint]. 2025 Feb 26:2025.02.23.639689. doi: 10.1101\/2025.02.23.639689.PMID:\u00a040027782<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-603 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Progenitor effect in the spleen drives early recovery via universal hematopoietic cell inflation<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-9 wp-block-post-content-is-layout-flow\">\n<p>Yogo T, Becker HJ, Kimura T, Iwano S, Kuchimaru T, Miyawaki A, Yokomizo T, Suda T, Iwama A, Yamazaki S.<\/p>\n\n\n\n<p>Cell Rep. 2025 Jan 25;44(2):115241. doi: 10.1016\/j.celrep.2025.115241. Online ahead of print.PMID:\u00a039864058\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-614 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">IL-1R1 and IL-18 Signals Regulate Mesenchymal Stromal Cells in an Aged Murine Model of Myelodysplastic Syndromes.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-10 wp-block-post-content-is-layout-flow\">\n<p>Kawano Y, Kawano H, LaMere MW, LaMere EA, Byun DK, McGrath K, Palis J, Bajaj J, Liesveld JL, Katayama Y,\u00a0Yamazaki S, Kapur R, Calvi LM, Ho TC, Becker MW.\u00a0<\/p>\n\n\n\n<p>Blood. 2025 Jan 22:blood.2024024818. doi: 10.1182\/blood.2024024818. Online ahead of print.PMID:\u00a039841001<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-720 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">2024<\/h5>\n\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-586 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Does old-to-young kidney transplantation rejuvenate old donor kidneys?\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-11 wp-block-post-content-is-layout-flow\">\n<p>Takahashi-Kobayashi M, Kawanishi K, Usui J,\u00a0Yamazaki S, Seshan SV, Yamagata K.\u00a0<\/p>\n\n\n\n<p>Histol Histopathol. 2024 Oct 7:18829. doi: 10.14670\/HH-18-829. Online ahead of print.PMID:\u00a039478629<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-583 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Preexisting senescent fibroblasts in the aged bladder create a tumor-permissive niche through CXCL12 secretion.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-12 wp-block-post-content-is-layout-flow\">\n<p>Meguro S, Johmura Y, Wang TW, Kawakami S, Tanimoto S, Omori S, Okamura YT, Hoshi S, Kayama E, Yamaguchi K, Hatakeyama S,\u00a0Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Kojima Y, Nakanishi M.<\/p>\n\n\n\n<p>Nat Aging. 2024 Sep 9. doi: 10.1038\/s43587-024-00704-1. Online ahead of print.PMID:\u00a039251867<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-581 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-13 wp-block-post-content-is-layout-flow\">\n<p>Kaito S, Aoyama K, Oshima M, Tsuchiya A, Miyota M, Yamashita M, Koide S, Nakajima-Takagi Y, Kozuka-Hata H, Oyama M, Yogo T, Yabushita T, Ito R, Ueno M, Hirao A, Tohyama K, Li C, Kawabata KC, Yamaguchi K, Furukawa Y, Kosako H, Yoshimi A, Goyama S, Nannya Y, Ogawa S, Agger K, Helin K,\u00a0Yamazaki S, Koseki H, Doki N, Harada Y, Harada H, Nishiyama A, Nakanishi M, Iwama A.\u00a0\u00a0<\/p>\n\n\n\n<p>Nat Commun. 2024 Aug 28;15(1):7359. doi: 10.1038\/s41467-024-50498-4.PMID:\u00a039198387\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-386 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">M2 macrophage-derived TGF-\u03b2 induces age-associated loss of adipogenesis through progenitor cell senescence.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-14 wp-block-post-content-is-layout-flow\">\n<p>Zeng X, Wang TW, Yamaguchi K, Hatakeyama S,\u00a0Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Johmura Y, Nakanishi M.<\/p>\n\n\n\n<p>Mol Metab. 2024 Jun;84:101943. doi: 10.1016\/j.molmet.2024.101943. Epub 2024 Apr 23.PMID:\u00a038657734<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-388 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Heart failure promotes multimorbidity through innate immune memory.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-15 wp-block-post-content-is-layout-flow\">\n<p>Nakayama Y, Fujiu K, Oshima T, Matsuda J, Sugita J, Matsubara TJ, Liu Y, Goto K, Kani K, Uchida R, Takeda N, Morita H, Xiao Y, Hayashi M, Maru Y, Hasumi E, Kojima T, Ishiguro S, Kijima Y, Yachie N,\u00a0Yamazaki S, Yamamoto R, Kudo F, Nakanishi M, Iwama A, Fujiki R, Kaneda A, Ohara O, Nagai R, Manabe I, Komuro I.\u00a0Sci Immunol. 2024 May 24;9(95):eade3814. doi: 10.1126\/sciimmunol.ade3814. Epub 2024 May 24.PMID:\u00a038787963<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-284 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Age-related changes in the hematopoietic stem cell pool revealed via quantifying the balance of symmetric and asymmetric divisions<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-16 wp-block-post-content-is-layout-flow\">\n<p>Kawahigashi T, Iwanami S, Takahashi M, Bhadury J, Iwami S,\u00a0Yamazaki S.<\/p>\n\n\n\n<p>PLoS One. 2024 Jan 29;19(1):e0292575. doi: 10.1371\/journal.pone.0292575. eCollection 2024.PMID:\u00a038285676\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-278 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Purging myeloma cell contaminants and simultaneous expansion of peripheral blood-mobilized stem cells<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-17 wp-block-post-content-is-layout-flow\">\n<p>Ishitsuka K, Nishikii H, Kimura T, Sugiyama-Finnis A,\u00a0Yamazaki S.<\/p>\n\n\n\n<p>Exp Hematol. 2024 Mar;131:104138. doi: 10.1016\/j.exphem.2023.104138. Epub 2023 Dec 25.PMID:\u00a038151170\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-266 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust CytotoxicityAgainst Small Cell Lung Cancer<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-18 wp-block-post-content-is-layout-flow\">\n<p>Kinoshita S, Ishii M, Ando J, Kimura T, Yamaguchi T, Harada S, Takahashi F, Nakashima K, Nakazawa Y, Yamazaki S, Ohshima K, Takahashi K, Nakauchi H, Ando M.<br>Cancer Res Commun. 2024 Mar 11;4(3):723-737. doi: 10.1158\/2767-9764.CRC-23-0259. PMID: 38380966; PMCID: PMC10926899.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-253 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Activated mesenchymal stem\/stromal cells promote myeloid cell differentiationvia CCL2\/CCR2 signaling<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-19 wp-block-post-content-is-layout-flow\">\n<p>Yamazaki S, Mabuchi Y, Kimura T, Suto EG, Hisamatsu D, Naraoka Y, Kondo A, Azuma Y, Kikuchi R, Nishikii H, Morishita S, Araki M, Komatsu N, Akazawa C. <\/p>\n\n\n\n<p>Stem Cell Reports. 2024 Mar 12;19(3):414-425. doi:10.1016\/j.stemcr.2024.02.002. Epub 2024 Feb 29. PMID: 38428413; PMCID: PMC10937152.<\/p>\n\n\n\n<p><\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-276 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">A novel Kit mutant rat enables hematopoietic stem cell engraftment without irradiation<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-20 wp-block-post-content-is-layout-flow\">\n<p>Iida R, Ishida S, Wang J, Hattori K, Yoshimi K,\u00a0Yamazaki S, Mashimo T.Iida R, Ishida S, Wang J, Hattori K, Yoshimi K,\u00a0Yamazaki S, Mashimo T.<\/p>\n\n\n\n<p>Exp Hematol. 2024 Apr;132:104174. doi: 10.1016\/j.exphem.2024.104174. Epub 2024 Feb 6.PMID:\u00a038331018<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-282 post type-post status-publish format-standard hentry category-publication-2 category-review\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Understanding genetic heterogeneity in gene-edited hematopoietic stem cell products<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-21 wp-block-post-content-is-layout-flow\">\n<p>Becker HJ,\u00a0Yamazaki S. <\/p>\n\n\n\n<p>Exp Hematol. 2024 Jan;129:104133. doi: 10.1016\/j.exphem.2023.11.007. Epub 2023 Nov 29.PMID:\u00a038036097<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-280 post type-post status-publish format-standard hentry category-publication-2 category-review\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Ex vivo expansion of human hematopoietic stem cells and clinical applications<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-22 wp-block-post-content-is-layout-flow\">\n<p>Sakurai M, Ishitsuka K, Becker HJ,\u00a0Yamazaki S.<\/p>\n\n\n\n<p>Cancer Sci. 2024 Mar;115(3):698-705. doi: 10.1111\/cas.16066. Epub 2024 Jan 14.PMID:\u00a038221718\u00a0Free PMC article.\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-722 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">2023<\/h5>\n\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-286 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Hyperactive Natural Killer cells in Rag2 knockout mice inhibit the development of acute myeloid leukemia<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-23 wp-block-post-content-is-layout-flow\">\n<p>Sugimoto E, Li J, Hayashi Y, Iida K, Asada S, Fukushima T, Tamura M, Shikata S, Zhang W, Yamamoto K, Kawabata KC, Kawase T, Saito T, Yoshida T,\u00a0Yamazaki S, Kaito Y, Imai Y, Denda T, Ota Y, Fukuyama T, Tanaka Y, Enomoto Y, Kitamura T, Goyama S. <\/p>\n\n\n\n<p>Commun Biol. 2023 Dec 21;6(1):1294. doi: 10.1038\/s42003-023-05606-3.PMID:\u00a038129572\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-289 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-24 wp-block-post-content-is-layout-flow\">\n<p>Li D, Johmura Y, Morimoto S, Doi M, Nakanishi K, Ozawa M, Tsunekawa Y, Inoue-Yamauchi A, Naruse H, Matsukawa T, Takeshita Y, Suzuki N, Aoki M, Nishiyama A, Zeng X, Konishi C, Suzuki N, Nishiyama A, Harris AS, Morita M, Yamaguchi K, Furukawa Y, Nakai K, Tsuji S,\u00a0<strong>Yamazaki S<\/strong>, Yamanashi Y, Shimada S, Okada T, Okano H, Toda T, Nakanishi M. \u00a0<\/p>\n\n\n\n<p>Nat Aging. 2023 Aug;3(8):1001-1019. doi: 10.1038\/s43587-023-00464-4. Epub 2023 Jul 20.PMID:\u00a037474791<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-291 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-25 wp-block-post-content-is-layout-flow\">\n<p>Becker HJ, Ishida R, Wilkinson AC, Kimura T, Lee MSJ, Coban C, Ota Y, Tanaka Y, Roskamp M, Sano T, Tojo A, Kent DG,\u00a0Yamazaki S.<\/p>\n\n\n\n<p>Cell Stem Cell. 2023 Jul 6;30(7):987-1000.e8. doi: 10.1016\/j.stem.2023.06.002. 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Epub 2021 Oct 8.PMID:\u00a034628050<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-561 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-33 wp-block-post-content-is-layout-flow\">\n<p>Harada S, Ando M, Ando J, Ishii M, Yamaguchi T,\u00a0Yamazaki S, Toyota T, Ohara K, Ohtaka M, Nakanishi M, Shin C, Ota Y, Nakashima K, Ohshima K, Imai C, Nakazawa Y,\u00a0Nakauchi H, Komatsu N.<\/p>\n\n\n\n<p><em>Mol Ther.<\/em>\u00a02022 Feb 2;30(2):534-549. doi: 10.1016\/j.ymthe.2021.10.006. Epub 2021 Oct 8.PMID:\u00a034628050<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-726 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">2021<\/h5>\n\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-557 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Immunohistological score of transcription factor 21 had a positive correlation with its urinary excretion and proteinuria in immunoglobulin A nephropathy.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-34 wp-block-post-content-is-layout-flow\">\n<p>Takahashi-Kobayashi M, Usui J, Yaguchi M,\u00a0Yamazaki S,\u00a0Kawamura T, Kaneko S, Seshan SV, Yamagata K.<\/p>\n\n\n\n<p><em>Histol Histopathol.<\/em>\u00a02021 Oct;36(10):1093-1098. doi: 10.14670\/HH-18-367. 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Epub 2021 Aug 12.PMID:\u00a034385178<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-553 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Non-conditioned bone marrow chimeric mouse generation using culture-based enrichment of hematopoietic stem and progenitor cells.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-37 wp-block-post-content-is-layout-flow\">\n<p>Ochi K, Morita M, Wilkinson AC, Iwama A,\u00a0Yamazaki S.\u00a0<\/p>\n\n\n\n<p><em>Nat Commun<\/em>. 2021 Jun 11;12(1):3568. doi: 10.1038\/s41467-021-23763-z.PMID:\u00a034117255\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-551 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Limited rejuvenation of aged hematopoietic stem cells in young\u00a0bone marrow niche.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-38 wp-block-post-content-is-layout-flow\">\n<p>Kuribayashi W, Oshima M, Itokawa N, Koide S, Nakajima-Takagi Y, Yamashita M,\u00a0Yamazaki S, Rahmutulla B, Miura F, Ito T, Kaneda A, Iwama A.<\/p>\n\n\n\n<p><em>J Exp Med.<\/em>\u00a02021 Mar 1;218(3):e20192283. doi: 10.1084\/jem.20192283.PMID:\u00a033231616<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-549 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">DHODH inhibition synergizes with DNA-demethylating agents in the treatment of myelodysplastic syndromes.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-39 wp-block-post-content-is-layout-flow\">\n<p>Kayamori K, Nagai Y, Zhong C, Kaito S, Shinoda D, Koide S, Kuribayashi W, Oshima M, Nakajima-Takagi Y, Yamashita M, Mimura N, Becker HJ, Izawa K,\u00a0Yamazaki S, Iwano S, Miyawaki A, Ito R, Tohyama K, Lennox W, Sheedy J, Weetall M, Sakaida E, Yokote K, Iwama A.\u00a0<\/p>\n\n\n\n<p><em>Blood Adv.<\/em>\u00a02021 Jan 26;5(2):438-450. doi: 10.1182\/bloodadvances.2020001461.PMID:\u00a033496740\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-728 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; 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Epub 2020 Nov 2.PMID:\u00a033037737\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-542 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-41 wp-block-post-content-is-layout-flow\">\n<p>Sato R, Reuter T, Hiranuma R, Shibata T, Fukui R, Motoi Y, Murakami Y, Tsukamoto H,\u00a0Yamazaki S, Liu K, Saitoh SI, Latz E, Miyake K.\u00a0<\/p>\n\n\n\n<p><em>Int Immunol.<\/em>\u00a02020 Nov 23;32(12):785-798. doi: 10.1093\/intimm\/dxaa055.PMID:\u00a032840578<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-544 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high\u00a0Cells In\u00a0Vivo.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-42 wp-block-post-content-is-layout-flow\">\n<p>Omori S, Wang TW, Johmura Y, Kanai T, Nakano Y, Kido T, Susaki EA, Nakajima T, Shichino S, Ueha S, Ozawa M, Yokote K, Kumamoto S, Nishiyama A, Sakamoto T,\u00a0Yamaguchi K, Hatakeyama S, Shimizu E, Katayama K, Yamada Y,\u00a0Yamazaki S, Iwasaki K, Miyoshi C, Funato H, Yanagisawa M, Ueno H, Imoto S, Furukawa Y, Yoshida N, Matsushima K, Ueda HR, Miyajima A, Nakanishi M.<\/p>\n\n\n\n<p><em>Cell Metab<\/em>. 2020 Nov 3;32(5):814-828.e6. doi: 10.1016\/j.cmet.2020.09.006. Epub 2020 Sep 18.PMID:\u00a032949498\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-540 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Activated HoxB4-induced Hematopoietic Stem Cells from Murine Pluripotent Stem Cells via Long-Term Programming.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-43 wp-block-post-content-is-layout-flow\">\n<p>Izawa K,\u00a0Yamazaki S, Becker HJ, Bhadury J, Kakegawa T, Sakaguchi M, Tojo A.\u00a0<\/p>\n\n\n\n<p><em>Exp Hematol.<\/em>\u00a02020 Sep;89:68-79.e7. doi: 10.1016\/j.exphem.2020.08.003. 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Epub 2020 Mar 12.PMID:\u00a032162097<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-534 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Long-term eradication of extranodal NK\/T cell lymphoma, nasal type, by induced pluripotent stem cell-derived Epstein-Barr virus-specific rejuvenated T cells\u00a0in vivo.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-46 wp-block-post-content-is-layout-flow\">\n<p>Ando M, Ando J,\u00a0Yamazaki S, Ishii M, Sakiyama Y, Harada S, Honda T, Yamaguchi T, Nojima M, Ohshima K, Nakauchi H, Komatsu N.\u00a0<\/p>\n\n\n\n<p><em>Haematologica.<\/em>\u00a02020 Mar;105(3):796-807. doi: 10.3324\/haematol.2019.223511. Epub 2019 Jul 11.PMID:\u00a031296577\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-532 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Long-term ex vivo expansion of mouse hematopoietic stem cells.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-47 wp-block-post-content-is-layout-flow\">\n<p>Wilkinson AC, Ishida R, Nakauchi H,\u00a0Yamazaki S.<\/p>\n\n\n\n<p><em>Nat Protoc.<\/em>\u00a02020 Feb;15(2):628-648. doi: 10.1038\/s41596-019-0263-2. 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font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Long-term eradication of extranodal NK\/T cell lymphoma, nasal type, by induced pluripotent stem cell-derived Epstein-Barr virus-specific rejuvenated T cells\u00a0in vivo.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-53 wp-block-post-content-is-layout-flow\">\n<p>Ando M, Ando J,\u00a0Yamazaki S, Ishii M, Sakiyama Y, Harada S, Honda T, Yamaguchi T, Nojima M, Ohshima K, Nakauchi H, Komatsu N.<\/p>\n\n\n\n<p><em>Haematologica.<\/em>\u00a02019 Jul 11. pii: haematol.2019.223511.2019.223511<\/p>\n\n\n\n<p><\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-518 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Mesenchymal-Epithelial Interactome Analysis Reveals Essential Factors Required for Fibroblast-Free Alveolosphere Formation.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-54 wp-block-post-content-is-layout-flow\">\n<p>Shiraishi\u00a0K, Shichino S, Ueha S, Nakajima T, Hashimoto S,\u00a0Yamazaki S, Matsushima K.<\/p>\n\n\n\n<p><em>iScience<\/em>.\u00a02019 Jan 25;11:318-333.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-732 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; 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font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-56 wp-block-post-content-is-layout-flow\">\n<p>Asada S, Goyama S, Inoue D, Shikata S, Takeda R, Fukushima T, Yonezawa T, Fujino T, Hayashi Y, Kawabata KC, Fukuyama T, Tanaka Y, Yokoyama A,\u00a0Yamazaki S, Kozuka-Hata H, Oyama M, Kojima S, Kawazu M, Mano H, Kitamura T.<\/p>\n\n\n\n<p><em>Nat Commun<\/em>. 2018 Jul 16;9(1):2733.\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-508 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-57 wp-block-post-content-is-layout-flow\">\n<p>Tadokoro Y, Hoshii T,\u00a0Yamazaki S, Eto K, Ema H, Kobayashi M, Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi H, Hirao A.\u00a0<\/p>\n\n\n\n<p><em>Cell Stem Cell<\/em>. 2018 May 3;22(5):713-725.e8.\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-512 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-58 wp-block-post-content-is-layout-flow\">\n<p>Si S, Nakajima-Takagi Y, Iga T, Tsuji M, Hou L, Oshima M, Koide S, Saraya A,\u00a0Yamazaki S, Takubo K, Kubota Y, Minamino T, Iwama A.\u00a0<\/p>\n\n\n\n<p><em>Exp Hematol<\/em>. 2018 Apr 27. pii: S0301-472X(18)30213-3.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-510 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-59 wp-block-post-content-is-layout-flow\">\n<p>Wilkinson AC, Morita M, Nakauchi H,\u00a0Yamazaki S.\u00a0<\/p>\n\n\n\n<p><em>Exp Hematol<\/em>. 2018 Apr 26. S0301-472 (18)30173-5.\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-506 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Physiological\u00a0Srsf2\u00a0P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-60 wp-block-post-content-is-layout-flow\">\n<p>Kon A,\u00a0Yamazaki S, Nannya Y, Kataoka K, Ota Y, Nakagawa MM, Yoshida K, Shiozawa Y, Morita M, Yoshizato T, Sanada M, Nakayama M, Koseki H, Nakauchi H, Ogawa S.\u00a0<\/p>\n\n\n\n<p><em>Blood.<\/em>\u00a02018 Feb 8;131(6):621-635.\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-734 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">2017<\/h5>\n\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-504 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">In\u00a0Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-61 wp-block-post-content-is-layout-flow\">\n<p>Tsukada M, Ota Y, Wilkinson AC, Becker HJ, Osato M, Nakauchi H,\u00a0Yamazaki S.<\/p>\n\n\n\n<p><em>Stem Cell Reports.\u00a0<\/em>2017 Oct 10;9(4):1024-1033.\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-502 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-62 wp-block-post-content-is-layout-flow\">\n<p>Ieyasu A, Ishida R, Kimura T, Morita M, Wilkinson AC, Sudo K, Nishimura T, Ohehara J, Tajima Y, Lai CY, Otsu M, Nakamura Y, Ema H, Nakauchi H,Yamazaki S.<\/p>\n\n\n\n<p>\u00a0<em>Stem Cell Reports<\/em>. 2017 Mar 14\u00a0;8(3):500-508.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-500 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Continuous cell supply from Krt7-expressing hematopoietic stem cells during native hematopoiesis revealed by targeted in vivo gene transfer method.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-63 wp-block-post-content-is-layout-flow\">\n<p>Tajima Y, Ito K, Umino A, Wilkinson AC, Nakauchi H,\u00a0Yamazaki S.<\/p>\n\n\n\n<p><em>Sci Rep.<\/em>\u00a02017 Jan 18\u00a0;7:40684.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-736 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Before 2016<\/h5>\n\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-498 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-64 wp-block-post-content-is-layout-flow\">\n<p>Taya Y, Ota Y, Wilkinson AC, Kanazawa A, Watarai H, Kasai M, Nakauchi H and\u00a0Yamazaki S.<\/p>\n\n\n\n<p><em>Science.\u00a0<\/em>Oct 20, 2016\u00a0354(6316):1152-1155.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-495 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenyous perivascular niche.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-65 wp-block-post-content-is-layout-flow\">\n<p><em>Chen JY, Miyanishi M, Wang SK,\u00a0Yamazaki S, Shnha R, Kao KS, Seita J, Sahoo D, Nakauchi H, Weissman IL.<\/em><\/p>\n\n\n\n<p><em>Nature<\/em>. 2016 Feb 11;530(7589):223-7.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-493 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">A Safeguard System for Induced Pluripotent Stem Cell Derived Rejuvenated T Cell Therapy.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-66 wp-block-post-content-is-layout-flow\">\n<p>Ando M, Nishimura T,\u00a0Yamazaki S, Yamaguchi T, Kawana-Tachikawa A, Hayama T, Nakauchi Y, Ando J, Ota Y, Takahashi S, Nishimura K, Ohtaka M, Nakanishi M, Miles JJ, Burrows SR, Brenner MK, Nakauchi H.\u00a0<\/p>\n\n\n\n<p><em>Stem Cell Reports.<\/em>\u00a02015 Oct 13;5(4): 597-608.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-491 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Reactive oxygen species in hematopoietic stem cells affect culture outcome under inflammatory conditions.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-67 wp-block-post-content-is-layout-flow\">\n<p>Ishida T,\u00a0Yamazaki S, Nakauchi H, Higashihara M, Otsu M.\u00a0<\/p>\n\n\n\n<p><em>Open Journal of Hematology<\/em>. 2015;6:6-7.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-489 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Effective treatment against severe Graft-versus-Host Disease with allele-specific anti-HLA monoclonal antibody in a humanized-mouse model.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-68 wp-block-post-content-is-layout-flow\">\n<p>Nakauchi Y,\u00a0Yamazaki S, Napier C S, Usui J, Ota Y, Takahashi S, Watanabe N, Nakauchi H.\u00a0<\/p>\n\n\n\n<p><em>Exp Hematol<\/em>. 2015 Feb;43(2):79-88.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-485 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Impaired hematopoietic differentiation of RUNX1 mutated induced pluripotent stem cells derived from FPD\/AML patients.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-69 wp-block-post-content-is-layout-flow\">\n<p>Sakurai M, Kunimoto H, Watanabe N, Fukuchi Y, Yuasa S,\u00a0Yamazaki S, Nishimura T, Sadahira K, Fukuda K, Okano H, Nakauchi H, Morita Y, Matsumura I, Kudo K, Ito E, Ebihara Y, Tsuji K, Harada Y, Harada H, Okamoto S, Nakajima H.<\/p>\n\n\n\n<p><em>Leukemia.<\/em>\u00a02014 Dec:28(12):2344-54.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-487 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Generation of recombination activating gene-1-deficient neonatal piglets: a model of T and B cell deficient severe combined immune deficiency.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-70 wp-block-post-content-is-layout-flow\">\n<p>Ito T, Sendai Y,\u00a0Yamazaki S,\u00a0Seki-Soma M, Hirose K, Watanabe M, Fukawa K, Nakauchi H.\u00a0<\/p>\n\n\n\n<p><em>PLoS One<\/em>. 2014 Dec 1;9(12):e113833.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-483 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">A melanocyte-melanoma precursor niche in sweat glands of volar skin.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-71 wp-block-post-content-is-layout-flow\">\n<p>Okamoto N, Aoto T, Uhara H,\u00a0Yamazaki S, Akutsu H, Umezawa A, Nakauchi H, Miyachi Y, Saida T, Nishimura EK.<\/p>\n\n\n\n<p><em>Pigment Cell Melanoma.\u00a0<\/em>2014 Nov;27(6):1039-50.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-480 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Gene Targeting Study Reveals Unexpected Expression of Brain Expressed X-linked 2 in Endocrine and Tissue Stem\/projenitor Cells in Mice.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-72 wp-block-post-content-is-layout-flow\">\n<p>Ito K,\u00a0Yamazaki S, Yamamoto R, Tajima Y, Yanagida A, Kobayashi T, Kato-Itoh M, Kakuta S, Iwakura Y, Nakauchi H, Kamiya A.\u00a0<\/p>\n\n\n\n<p>\u00a0<em>J Biol Chem.<\/em>\u00a02014 Oct 24;289(43):29892-911.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-478 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Generation of Mouse Functional Oocytes in Rat by Xeno-Ectopic Transplantation of Primorial Germ Cells.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-73 wp-block-post-content-is-layout-flow\">\n<p>Hayama T, Yamaguchi T, Kato-Itoh M, Hamanaka S, Kawarai M, Sanbo M, Tamura C, Lee YS, Yanagida A, Murayama H, Mizuno N, Umino A, Sato H,\u00a0Yamazaki S, Masaki H, Kobayashi T, Hirabayashi M, Nakauchi H.\u00a0<\/p>\n\n\n\n<p><em>Biol Reprod.<\/em>\u00a02014 Oct;91(4):89.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-476 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-74 wp-block-post-content-is-layout-flow\">\n<p>Kazuki Y, Yakura Y, Abe S, Osaki M, Kajitani N, Kazuki K, Takehara S, Honma K, Suemori H,\u00a0Yamazaki S, Sakuma T, Toki T, Shimisu R, Nakauchi H, Yamamoto T, Oshimura M.\u00a0<\/p>\n\n\n\n<p><em>Sci Rep.<\/em>\u00a02014 Aug 27;4: 6136.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-474 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Stage-specific roles for Cxcr4 signaling in murine hematopoietic stem\/progenitor cells in the process of bone marrow repopulation.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-75 wp-block-post-content-is-layout-flow\">\n<p>Lai CY,\u00a0Yamazaki S,\u00a0Okabe M, Suzuki S, Maeyama Y, Iimura Y, Onodera M, Kakuta S, Iwakura Y, Nojima M, Otsu M, Nakauchi H.\u00a0<\/p>\n\n\n\n<p><em>Stem cells.<\/em>\u00a02014 Jul;32(7):1929-42.\u00a0<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-472 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Clock gene Bmal1 is dispensable for intrinsic properties of murine hematopoietic stem cells.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-76 wp-block-post-content-is-layout-flow\">\n<p>Ieyasu A, Tajima Y, Shimba S, Nakauchi H,\u00a0Yamazaki S<\/p>\n\n\n\n<p><em>J Negat Biomed.<\/em>\u00a02014 Mar 8;13: 4.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-470 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">The TIF1beta-HP1 System Maintains Transcriptional Integrity of Hematopoietic Stem Cells.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-77 wp-block-post-content-is-layout-flow\">\n<p>Miyagi S, Koide S, Saraya A, Wendt GR, Oshima M, Konuma T,\u00a0Yamazaki S,\u00a0Mochizuki-Kashio M, Nakajima-Takagi Y, Wang C, Chiba T, Kitabayashi I, Nakauchi H, Iwama A.\u00a0<\/p>\n\n\n\n<p><em>Stem Cell Reports.<\/em>\u00a02014 Jan 23;2(2):145-52.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-468 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Immortalization of erythroblast by c-Myc and Bcl-xl enables large-scale erythrocyte production from human pluripotent stem cells.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-78 wp-block-post-content-is-layout-flow\">\n<p>Hirose S, Takayama N, Nakamura S, Nagasawa K, Ochi K, Hirata S,\u00a0Yamazaki S,\u00a0Yamaguchi T, Otsu M, Sano S, Takahashi N, Sawaguchi A, Ito M, Kato T, Nakauchi H, Eto K.<\/p>\n\n\n\n<p><em>Stem Cell Reports.\u00a0<\/em>2013 Dec 5;1(6):499-508.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-466 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-79 wp-block-post-content-is-layout-flow\">\n<p>Suzuki N,\u00a0Yamazaki S, Yamaguchi T, Okabe M, Masaki H, Takaki S, Otsu M and Nakauchi H.<\/p>\n\n\n\n<p><em>Mol Ther.<\/em>\u00a02013 Jul;21(7): 1424-31.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-462 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Development of an all in one inducible lentiviral vector for gene specific analysis of reprogramming.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-80 wp-block-post-content-is-layout-flow\">\n<p>Yamaguchi T, Hamanaka S, Kamiya A, Okabe M, Kawarai M, Wakiyama Y, Umino A, Hayama T, Sato H, Lee YS, Kato-Itoh M, Kobayashi T,\u00a0Yamazaki S\u00a0and Nakauchi H.\u00a0<\/p>\n\n\n\n<p><em>PLoS One<\/em>. 2012;7(7): e41007.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-464 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Bmi-1 confers resistance to oxidative stress on hematopoietic stem cells.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-81 wp-block-post-content-is-layout-flow\">\n<p>Nakamura S, Oshima M, Yuan J, Saraya A, Miyagi S, Konuma T,\u00a0Yamazaki S, Osawa M, Nakauchi H, Koseki H and Iwama A.<\/p>\n\n\n\n<p><em>\u00a0PLoS One<\/em>. 2012 May;7(5):e36209.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-460 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Lethal myelofibrosis induced by Bmi-1 deficient hematopoietic stem cells unveils a tumor suppressor function of the polycomb group genes.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-82 wp-block-post-content-is-layout-flow\">\n<p>Oguro H, Yuan J, Tanaka S, Miyagi S, Mochizuki-Kashio M, Ichikawa H,\u00a0Yamazaki S, Koseki H, Nakauchi H and Iwama A.<\/p>\n\n\n\n<p><em>J Exp Med<\/em>. 2012 Mar 12;209(3):445-454.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-457 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk\/Sh2b3 via Bcl-xl.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-83 wp-block-post-content-is-layout-flow\">\n<p>Suzuki N,\u00a0Yamazaki S,\u00a0Ema H, Yamaguchi T, Nakauchi H, and Nakauchi H.<\/p>\n\n\n\n<p><em>Exp Hematol<\/em>. 2012 Feb;40, 166-174.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-455 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Non-myelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-84 wp-block-post-content-is-layout-flow\">\n<p>Yamazaki S,\u00a0Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, and Nakauchi H.<\/p>\n\n\n\n<p><em>Cell<\/em>. 2011 Nov 23;147(5) 1146-1158.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-453 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Generation of germline-competent rat induced pluripotent stem cells.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-85 wp-block-post-content-is-layout-flow\">\n<p>Hamanaka S, Yamaguchi T, Kobayashi T, Kato-Itoh M,\u00a0Yamazaki S, Sato H, Umino A, Wakiyama Y, Arai M, Sanbo M, Hirabayashi M,\u00a0Nakauchi H.\u00a0<\/p>\n\n\n\n<p><em>PLoS One<\/em>. 2011 Jul 15;6(7):e22008.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-451 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Hair follicle stem cells provide a functional niche for melanocyte stem cells.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-86 wp-block-post-content-is-layout-flow\">\n<p>Tanimura S, Tadokoro Y, Inomata K, Binh NT, Nishie W,\u00a0Yamazaki S, Nakauchi H, Tanaka Y, McMillan JR, Sawamura D, Yancey K, Shimizu H, Nishimura EK.<\/p>\n\n\n\n<p><em>Cell Stem Cell<\/em>. 2011 Feb 4;8(2):177-87.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-449 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta1-mediated growth suppression in adult T-cell leukemia\/lymphoma.\u00a0<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-87 wp-block-post-content-is-layout-flow\">\n<p>Nakahata S,\u00a0Yamazaki S, Nakauchi H, Morishita K.<\/p>\n\n\n\n<p><em>Oncogene<\/em>. 2010 Jul 22;29(29):4157-69.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-447 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">TIM1 is an endogenous ligand for LMIR5\/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia\/reperfusion injury.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-88 wp-block-post-content-is-layout-flow\">\n<p>Yamanishi Y, Kitaura J, Izawa K, Kaitani A, Komeno Y, Nakamura M,\u00a0Yamazaki S, Enomoto Y, Oki T, Akiba H, Abe T, Komori T, Morikawa Y, Kiyonari H, Takai T, Okumura K, Kitamura T.<\/p>\n\n\n\n<p><em>J Exp Med<\/em>. 2010 Jul 5;207(7): 1501-11.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><li class=\"wp-block-post post-445 post type-post status-publish format-standard hentry category-publication-2\">\n<h5 style=\"padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:0px;margin-right:0px;margin-bottom:0px;margin-left:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.469), 20px);font-style:normal;font-weight:700;line-height:0.9;text-transform:uppercase;\" class=\"wp-block-post-title\">Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo.<\/h5>\n\n<div style=\"min-height:0px; font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);font-style:normal;font-weight:400;line-height:1;\" class=\"entry-content wp-block-post-content is-layout-flow wp-container-core-post-content-is-layout-89 wp-block-post-content-is-layout-flow\">\n<p>Takizawa H, Nishimura S, Takayama N, Oda A, Nishikii H, Morita Y, Kakinuma S,\u00a0Yamazaki S,\u00a0Okamura S, Tamura N, Goto S, Sawaguchi A, Manabe I, Takatsu K, Nakauchi H, Takaki S, Eto K.\u00a0<\/p>\n\n\n\n<p><em>J Clin Invest.<\/em>\u00a02010 Jun;120(1):179-90.<\/p>\n<\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/li><\/ul><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Publications<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/dcr-imsut.com\/index.php\/wp-json\/wp\/v2\/pages\/13"}],"collection":[{"href":"https:\/\/dcr-imsut.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/dcr-imsut.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/dcr-imsut.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dcr-imsut.com\/index.php\/wp-json\/wp\/v2\/comments?post=13"}],"version-history":[{"count":26,"href":"https:\/\/dcr-imsut.com\/index.php\/wp-json\/wp\/v2\/pages\/13\/revisions"}],"predecessor-version":[{"id":690,"href":"https:\/\/dcr-imsut.com\/index.php\/wp-json\/wp\/v2\/pages\/13\/revisions\/690"}],"wp:attachment":[{"href":"https:\/\/dcr-imsut.com\/index.php\/wp-json\/wp\/v2\/media?parent=13"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}